KRMC Front Desk Scripts

4/16/18

 

OVERVIEW: How are these scripts used?

Using the talking points below, the front desk needs to:

1. Determine the caller’s interest or concern
2. Answer questions using treatment-specific talking points based on the doctor and treatment the caller mentions
3. Reinforce the KRMC Difference

 

Once familiar with the talking points below, the front desk should determine which talking point is most useful in a given situation. The front desk does not need to use every talking point on every call — but rather use the talking points as a resource to answer questions and position KRMC as the research-driven leader in stem cell therapy.

 

 

Table of Contents

Phone Script                        

The KRMC Difference                

Adipose (SVF) (KRMC use)       

PRP                               

Cord                                

Wharton’s Jelly                

Amnion                       

Bone Marrow                        

 

 

 

Phone Script

First:

1. Identify company
2. Identify source or type of procedure
3. View description of the KRMC DIFFERENCE and Source/Treatment for talking points

 

Thank you for your call. We are familiar with ______________ <NAME OF DOCTOR OR TREATMENT>. The type of stem cell procedure they do uses ______________ <TYPE / ORIGIN OF CELLS>.

 

Our in-house research and clinical teams have studied all of the stem cell treatments available. We have found that _____________ stem cells are less effective because:

• Talking point 1
• Talking point 2
• Talking point 3

 

Because of these risks and the lack of effectiveness of ________________, we don’t offer this to our patients.

 

This is why KRMC uses your own stem cells. Our research shows that your own stem cells are the safest, most effective treatment choice for your body and healing.

<ADD IN ADDITIONAL TALKING POINTS AS NEEDED.>

 

Do you have any other questions?

 

Please feel free to call back anytime. We want to make sure you have all of the facts and are being safe with the treatment you choose.

 

Can I send you an email with more information and some questions to consider as you decide on the treatment that’s right for you?

The KRMC Difference

1. Why We Only Use Your Own Stem Cells?

Our research shows that using your own stem cells is the safest, most effective treatment choice for your body and healing.

• Our in-house science team and our doctors have researched the many types of stem cells available today. We have also drawn on research from the US National Library of Medicine and the National Institutes of Health.
• Based on this research, we have determined that using your own stem cells accelerates your body’s natural ability to heal itself.
• We use peer-reviewed research and science while others out there are using marketing and costs that appear lower — but that add up fast becauses they are less effective.

 

2. How Does Using Your Own Stem Cells Work?

We use stem cells that your body creates and stores naturally in fatty deposits because they are plentiful and easy to collect.

• These stem cells are called Adipose stem cells.
• They are “blank” cells that your body creates to replace dying cells or heal damaged tissue.

Our doctors collect these naturally occurring stem cells in a nearly painless procedure.

• These cells are plentiful and are easy to collect and re-introduce into the areas of your body that need healing.
• Once injected your stem cells get to work — regenerating healthy cells and accelerating your body’s natural ability to heal itself.
• It’s that simple.

 

3. How is this different that other types of Stem Cells?

• There are riskier, more painful and less-effective stem cell treatments out there.
• Like I said, they are less-effective and we do not use them becauses of the risks and poor results.
• We use your own stem cells because they are safer and more effective — and because your own stem cells accelerate your body’s natural ability to heal itself.  
• Here’s what our research has show us about ______________. <Insert the name of the treatment caller is referencing and jump to that information below>

Adipose (KRMC: SVF)

1. Does the Product contain living stem cells?

• Yes. KRMC uses Adipose stem cells collected from naturally occuring fat deposits in your body.
• Adipose (fat) contains 500 to 2,000 times more stem cells than bone marrow.
• https://www.ncbi.nlm.nih.gov/pubmed/23570660 

 

2. Does it use your own stem cells?

• Yes.

 

3. Does it require one or multiple visits?

• Unlike most other stem cell treatments, KRMC includes treatment includes multiple sites a single fee.
• For example, both knees and an elbow could be treated during one visit at no additional charge.
• It’s important to understand this if you are comparing costs.

• Most other treatments available charge you for each site treated.
• So a cost that may sound lower can rise very quickly when you actually add up multiple treatments.

 

4. Is IV injection available?

• Yes.

 

5. Specialists injecting with u/s c-arm guidance?

• Yes. KRMC uses the latest diagnostic imaging tools, including ultrasound and fluoroscopy, to ensure the safe and proper injection of cells.

 

6. IRB?

• Yes. <NEED MORE INFO ON THIS FROM KEN AND JOHN>

 

7. Is there a published safety study?

• Yes. There have been multiple studies with patients monitored for up to five years.
• The results show that is both safe and effective.
• KRMC treatments use SVF, which has been shown to be as safe or safer than treatments for arthritis.
• http://journals.sagepub.com/doi/abs/10.1177/0748806817691152 

 

 

8. Is there a published efficacy study?

• Yes. Multiple studies showing efficacy beyond 24 months.
• https://www.globalsciencejournals.com/article/10.7603%2Fs40730-014-0002-9
• https://www.sciencedirect.com/science/article/pii/S2452318616300733?via%3Dihub

 

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PRP

1. Does the Product contain living stem cells?

• There are virtually no living stem cells in PRP, which seriously limits PRP’s effectiveness as a stem cell treatment.
• We do use PRP for other purposes and I’d be happy to tell you more about those treatments.

• PRP boosts the efficacy of stem cell treatments and is therefore a strong companion treatment that we recommend.

• A culture needs 3-5 weeks to get significant numbers of stem cells.
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367504/pdf/sctm_20140150.pdf 

 

2. Does it use your own stem cells?

• Yes, PRP uses your own stem cells — but the numbers are very low and therefore not the most effective stem cell treatment.

 

3. Does PRP require one or multiple visits?

• One PRP kit can typically treat multiple smaller lesions or one large one. So, depending on the treatment need, you may require multiple visits and treatments.

 

4. Is IV injection available?

• An IV is not advisable. Your blood platelets can clot and injecting a clot IV is NOT advisable.

 

5. Specialists injecting with u/s c-arm guidance?

• This is unknown at this time.

 

6. IRB?

• This is unknown at this time.

 

7. Is there a published safety study?

• Yes, there have been multiple studies of PRP that show it to be safe. In fact, we find that it is as as safe as other intra-articular injections.
• https://www.ncbi.nlm.nih.gov/pubmed/28012636 

 

8. Is there a published efficacy study?

• Yes, there have been multiple studies that have shown PRP can be effective up to 12 months.
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260061/pdf/13018_2017_Article_521.pdf

Cord

1. Does the Product contain living stem cells?

• There are virtually zero living stem cells in this treatment.
• There have been no peer-reviewed publications. Independent analysis revealed no living cells.
• In freeze-dried cord stem cells (lyophilized) ALL cells were dead.
• You should definitely ask about freezing stem cells with what’s called cryoprotectants.

• When frozen without cryoprotectant then virtually all cells are dead.
• Cord stem cells frozen with DMSO (dimethyl sulfoxide) as cryoprotectant run real risks — including death. DMSO is believed to be the main cause of adverse reactions and many studies recommend depleting DMSO before cell infusion.  

• https://www.ncbi.nlm.nih.gov/pubmed/19590176 

 

2. Does it use your own stem cells?

• You should know that cord stem cells comes from a donor — an anonymous donor.
• Cord stem cells have potential for:

• Communicable disease transmission
• Genetic disease transmission. Scarily, some DNA of injected cells will be incorporated into the host)
• Graft-vs-host disease
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255242/pdf/bcj201114a.pdf 

 

3. Does it require one or multiple visits?

• Yes, this treatment requires may require multiple visits.
• And each treatment on a different part of your body is a separate charge.
• So, if you wanted 2 knees the price would be double the cost of one knee.

 

4. Is IV injection available?

• Manufacturers of these products advise against giving IV injections.

 

5. Specialists injecting with u/s c-arm guidance?

• This is unknown at this time.

 

6. IRB?

• This is unknown at this time.

 

7. Is there a published safety study?

• At this time we are unaware of any.

 

8. Is there a published efficacy study?

• At this time we are unaware of any.

 

 

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Wharton’s Jelly

1. Does the Product contain living stem cells?

• There are no peer-reviewed publications BUT independent analysis revealed no living cells.

• In freeze-dried cord stem cells (lyophilized) ALL cells were dead.
• You should definitely ask about freezing stem cells with what’s called cryoprotectants.

• When frozen without cryoprotectant then virtually all cells are dead.
• Cord stem cells frozen with DMSO (dimethyl sulfoxide) as cryoprotectant run real risks — including death. DMSO is believed to be the main cause of adverse reactions and many studies recommend depleting DMSO before cell infusion.  

• https://www.ncbi.nlm.nih.gov/pubmed/19590176 

 

2. Does it use your own stem cells?

• This product comes from a donor — an anonymous donor and that comes with risks.
• Stem cells from Wharton’s Jelly have the potential for

• Communicable disease transmission
• Genetic disease transmission (some DNA of injected cells will incorporate into the host)
• Graft-vs-host disease

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255242/pdf/bcj201114a.pdf 

 

3. Does it require one or multiple visits?

• Yes, this treatment requires may require multiple visits.
• And each treatment on a different part of your body is a separate charge.
• So, if you wanted 2 knees the price would be double the cost of one knee.

 

4. Is IV injection available?

• Manufacturers of these products advise against giving IV injections

 

5. Specialists injecting with u/s c-arm guidance?

• This is unknown at this time.

6. IRB?

• This is unknown at this time.

 

7. Is there a published safety study?

• This is unknown at this time.

 

8. Is there a published efficacy study?

• This is unknown at this time.

 

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Amnion

1. Does the Product contain living stem cells?

• There are no peer-reviewed publications BUT independent analysis revealed no living cells.

• In freeze-dried cord stem cells (lyophilized) ALL cells were dead.
• You should definitely ask about freezing stem cells with what’s called cryoprotectants.

• When frozen without cryoprotectant then virtually all cells are dead.
• Cord stem cells frozen with DMSO (dimethyl sulfoxide) as cryoprotectant run real risks — including death. DMSO is believed to be the main cause of adverse reactions and many studies recommend depleting DMSO before cell infusion.  

• https://www.ncbi.nlm.nih.gov/pubmed/19590176 

 

2. Does it use your own stem cells?

• This product comes from a donor — an anonymous donor and that comes with risks.
• Stem cells from Wharton’s Jelly have the potential for

• Communicable disease transmission
• Genetic disease transmission (some DNA of injected cells will incorporate into the host)
• Graft-vs-host disease

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255242/pdf/bcj201114a.pdf 

 

3. Does it require one or multiple visits?

• Yes, this treatment requires may require multiple visits.
• And each treatment on a different part of your body is a separate charge.
• So, if you wanted 2 knees the price would be double the cost of one knee.

 

4. Is IV injection available?

• Manufacturers of these products advise against giving IV injections

 

5. Specialists injecting with u/s c-arm guidance?

• This is unknown at this time.

6. IRB?

• This is unknown at this time.

 

7. Is there a published safety study?

• This is unknown at this time.

 

8. Is there a published efficacy study?

• This is unknown at this time.

 

 

 

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Bone Marrow

1. Does the Product contain living stem cells?

• Yes. But bone marrow contains very few mesenchymal stem cells, which are the most abundant and effective stem cells.
• Mesenchymal stem cells are the most abundant and useful stem cells — and are the type of stem cells we collect and use here at KRMC.

 

2. Does it use your own stem cells?

• Yes.

3. Does it require one or multiple visits?

• It typically requires multiple visits because there are a limited number of stem cells in bone marrow.
• As a result, treatments with bone marrow stem cells only treat one part of the body at a time.  
• Even with this, they typically require multiple visits to treat one structure.
• So, this treatment is sometimes less expense up-front, but quickly becomes more expensive due to the need for multiple visits or treatments.
• In addition, the collection of stem cells from bone marrow is typically more painful.

 

4. Is IV injection available?

• No. Bone marrow concentrate should not be injected by IV.

 

5. Specialists injecting with u/s c-arm guidance?

• This is unknown at this time.

 

6. IRB?

• This is unknown at this time.

 

7. Is there a published safety study?

• Yes there are.
• Other than the pain associated with BM aspiration, the procedure appears to be safe.
• https://link.springer.com/article/10.1007%2Fs00264-016-3162-y

 

8. Is there a published efficacy study?

• There are mixed results using bone marrow stem cell concentrate.
• Some show positive effects while others show no improvement compared with placebo studies.
• https://www.ncbi.nlm.nih.gov/pubmed/26089699
• https://www.ncbi.nlm.nih.gov/pubmed/27566242